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recS [2019-08-07 08:18:00]

ATP-dependent DNA helicase

locus

BSU_23020

6.23

56.34 kDa

protein length

496 aa Sequence Blast

gene length

1491 bp Sequence Blast

function

replication reactivation pathway

product

ATP-dependent DNA helicase

essential

synonyms

recS,ypbC

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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categories

[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]

[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]

Gene

Coordinates

2,406,922 2,408,412

The protein

Protein family

[SW|helicase family] (according to UniProt)

Paralogous protein(s)

[protein|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|RecQ]

Structure

[PDB|4Q47] ([protein|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|RecQ] from Deinococcus radiodurans, corresponds to aa 8 ... 394, 38% identity) [pubmed|25243132]

[SW|Localization]

cytoplasm (according to UniProt)

Biological materials

Mutant

1A893 (no resistance), [Pubmed|16020779], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A893&Search=1A893 BGSC]

BKE23020 ([gene|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|recS]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE23020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAACTGATATAACGTTTGCT, downstream forward: _UP4_TGAAACAGCAAAAAGATTAT

BKK23020 ([gene|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|recS]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK23020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAACTGATATAACGTTTGCT, downstream forward: _UP4_TGAAACAGCAAAAAGATTAT

References

Reviews

12427530,21047263,22933559

Original publications

17853894,25246477,25243132